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Allele : Pten<tm3.1Gle> phosphatase and tensin homolog; targeted mutation 3.1, Gustavo Leone
Primary Identifier  MGI:5806109 Allele Type  Targeted
Attribute String  Not Specified Gene  Pten
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 8 was replaced with a modified one in which a T to G point mutation results in the amino acid substitution of valine for phenylalanine at position 341 (F341V). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted upstream of the modified exon.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Pten<FV>,
  • Pten<FV>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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