Primary Identifier | MGI:5806150 | Allele Type | Endonuclease-mediated |
Attribute String | Hypomorph | Gene | Ica1l |
Strain of Origin | (C57BL/6 x CBA)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas technology targeted exon 2 to generate a knock-out allele lacking 23 nucleotides. Western blot analysis confirmed an 80% reduction in protein levels in the testes. |