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Allele : Tg(Slc6a11-cre/ERT2)1Khakh transgene insertion 1, Baljit Khakh
Primary Identifier  MGI:5806574 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Slc6a11-cre/ERT2)1Khakh
Strain of Origin  FVB/N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The transgene contains the entire solute carrier family 6 (neurotransmitter transporter GABA) member 11 locus (Slc6a11 [GAT3 or Gabt4]), as well as ~48 kbp 5' (centromeric) flanking region and ~36 kbp 3' (telomeric) flanking region from BAC RP23-470B21. Using homologous recombination/BAC recombineering, a CreER cDNA sequence followed by an SV40 polyadenylation signal was inserted into exon 1 of the BAC Slc6a11 gene immediately preceding the translation initiation codon. No other loci on the BAC were altered. Unstated number of founder lines with germline transmission are generated. A founder line #1 was established and characterized.
  • mutations:
  • Insertion
  • synonyms:
  • GAT3-Cre/ERT2 BAC,
  • Slc6a11-Cre/ERT2 BAC,
  • GAT3-Cre/ERT2 BAC,
  • Slc6a11-Cre/ERT2 BAC
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

2 Publication categories





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