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Allele : Tg(Thy1-SNCA*E57K)16Ema transgene insertion 16, Eliezer Masliah
Primary Identifier  MGI:5806788 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1-SNCA*E57K)16Ema
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The human alpha-synuclein bearing the oligomer-prone E57K mutation is under the control of neuronal mouse Thy1 promoter. Three lines were generated. Lines 9 and 16 are high expressers, and line 54 is a lower expressing line. Size exclusion chromatography confirmed the formation of oligomeric alpha-synuclein.
  • mutations:
  • Insertion
  • synonyms:
  • mThy1-alpha-syn E57K tg,
  • alpha-syn E57K tg,
  • alpha-syn E57K tg,
  • mThy1-alpha-syn E57K tg
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories





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