Primary Identifier | MGI:5806327 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Cd8a |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to T transversion at base pair 71,373,872 (v38) on chromosome 6, or base pair 446 in the GenBank genomic region NC_000072. The mutation affects nucleotide 446 of Cd8a mRNA variants 1 (NM_001081110.2) and 2 (NM_009857.1) within exon 1 of 5 total exons and exon 1 of 4 total exons, respectively. The mutation results in an aspartic acid (D) to valine (V) substitution at position 107 (D107V) of both variants. |