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Allele : Cd8a<m2Btlr> CD8 subunit alpha; mutation 2, Bruce Beutler

Primary Identifier  MGI:5806327 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Cd8a
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced A to T transversion at base pair 71,373,872 (v38) on chromosome 6, or base pair 446 in the GenBank genomic region NC_000072. The mutation affects nucleotide 446 of Cd8a mRNA variants 1 (NM_001081110.2) and 2 (NM_009857.1) within exon 1 of 5 total exons and exon 1 of 4 total exons, respectively. The mutation results in an aspartic acid (D) to valine (V) substitution at position 107 (D107V) of both variants.
  • mutations:
  • Single point mutation
  • synonyms:
  • wenzhou,
  • wenzhou
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele