|  Help  |  About  |  Contact Us

Allele : Lyn<M3Btlr> LYN proto-oncogene, Src family tyrosine kinase; mutation 3, Bruce Beutler

Primary Identifier  MGI:5806331 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Lyn
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced G to T transversion at base pair 3,745,330 (v38) on chromosome 4, or base pair 67,210 in the GenBank genomic region NC_000070. The mutation corresponds to residue 546 in the mRNA sequence NM_001111096 (variant 1) within exon 5 of 13 total exons as well as residue 483 in the mRNA sequence NM_10747 (variant 2) within exon 5 or 13 total exons. The mutation results in a tryptophan (W) to cysteine (C) substitution at position 99 (W99C) in the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Pacific,
  • Pacific
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories