Primary Identifier | MGI:5811153 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-MYC,-OVAL)#Gtgm |
Strain of Origin | C57BL/6J or C57BL/6J x (C57BL/6J x DBA/2)F1 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene contains a tetracycline responsive element, comprising seven tandem copies of the tetracycline operator (tetO), driving bidirectional expression of cDNAs encoding human MYC (melanocytomatosis oncogene; also called c-myc)(exons 2-3) and cytosolic chicken ovalbumin (OVAL; also called SERPINB14) from oppositely-oriented human cytomegalovirus (CMV) minimal promoters. |