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Allele : Trem2<em3Adiuj> triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 3, MODEL-AD Center

Primary Identifier  MGI:5816607 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Trem2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The allele was generated by injecting cas9 nuclease and a single guide RNA designed to introduce a Y38C point mutation into the gene.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Trem2 Y38C KI,
  • Trem2 Y38C KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories