Primary Identifier | MGI:5817987 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Bap1 |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Zinc finger nuclease mediated targeted mutation changed glutamine codon 683 (CAG) in exon 16 to a stop codon (TAG) (p.Q683*). This mutation is the equivalent of the human p.Q684* mutation found in a family with malignant mesothelioma. |