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Allele : Bap1<em3Test> Brca1 associated protein 1; endonuclease-mediated mutation 3, Joseph R Testa

Primary Identifier  MGI:5817987 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Bap1
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  Zinc finger nuclease mediated targeted mutation changed glutamine codon 683 (CAG) in exon 16 to a stop codon (TAG) (p.Q683*). This mutation is the equivalent of the human p.Q684* mutation found in a family with malignant mesothelioma.
  • mutations:
  • Single point mutation
  • synonyms:
  • Bap1<L>,
  • Bap1<L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele