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Allele : Tg(Gcg-cre/ERT2)1Asp transgene insertion 1, Andrew S Peterson

Primary Identifier	MGI:5818288	Allele Type	Transgenic
Attribute String	Inducible, Recombinase	Gene	Tg(Gcg-cre/ERT2)1Asp
Strain of Origin	Not Specified	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

A BAC transgene spanning 100 kb of the Gcg locus was engineered by replacing the ATG and first coding exon of Gcg with a cDNA encoding a tamoxifen-inducible Cre-estrogen receptor fusion protein (Cre/ERT2). No line information was provided.

mutations:
Insertion

synonyms:
GcgCreERT2,
GcgCreERT2

earliestPublication:
Solloway MJ, et al. (2015) Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of alpha-Cell Mass. Cell Rep 12(3):495-510

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

2 Publication categories

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