Primary Identifier | MGI:5818716 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Wap-TDGF1)1Dsal |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Mice bearing this transgene express human teratocarcinoma-derived growth factor 1 (TDGF1; also called Cripto-1 or CR-1) under control of the promoter of the whey acidic protein gene (Wap). The transgene contains the Wap promoter followed by the coding sequence of human TDGF1 cDNA, flanked by 220 bp of 5'- and 110 bp of 3'- untranslated region (UTR) DNA, and the bovine growth hormone polyadenylation signal. |