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Allele : Tyr<em9Ove> tyrosinase; endonuclease-mediated mutation 9, Paul Overbeek

Primary Identifier  MGI:5818875 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Tyr
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology was used to generate two deletions in the promoter region. The first deletion, of 16 bp, encompasses base pairs -95 through -80 relative to the translation initiating ATG. The second deletion, of 649 bp, encompasses base pairs -809 through -160 relative to the ATG start codon.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • tyro promo (-50/-100)-3,
  • OVE modTP-9,
  • OVE modTP-9,
  • tyro promo (-50/-100)-3
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories