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Allele : 4930447C04Rik<em1Amp> RIKEN cDNA 4930447C04 gene; endonuclease-mediated mutation 1, Alberto M Pendas

Primary Identifier  MGI:5823358 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  4930447C04Rik
Strain of Origin  (C57BL/6J x CBA/J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 124bp deletion (GRCm39:chr12:72963494-72963618) that includes part of exon 2, intron 2 and part of exon 3 was created by CRISPR/Cas9 genome editing using sgRNAs (targeting CACCGATCTGTTTGTCAGTTTGGAC, AAACGTCCAAACTGACAAACAGATC, CACCGTACTTATGTCTTGCTCATAC and AAACGTATGACAAGACATAAGTAC). Spermatocytes from homozygous mice showed no protein expression by immunofluorescence studies, suggesting that this is a null allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Six6os1<->,
  • Six6os1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories