| Primary Identifier | MGI:5824089 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(SV40-Nfkb*-lacZ)17814Pabk |
| Strain of Origin | C3H x BALB/c | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | An NF-kappaB responsive minigene containing three tandem HIV-derived kappaB binding element repeats was placed proximal to a minimal promoter derived from SV40. Upon NF-kappaB binding, this construct drives expression of beta-galactosidase that was modified to include an SV40 T-antigen-derived nuclear localization sequence. 10 founder lines were generated, and three founder lines (17814, 17815, and 17819) were kept and studied further. |