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Allele : Bloc1s2<tm1Wli> biogenesis of lysosomal organelles complex-1, subunit 2; targeted mutation 1, Wei Li
Primary Identifier  MGI:5824713 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bloc1s2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked PGK-neomycin selection cassette replaced exons 1-4 of the gene. Immunoblotting analysis showed that protein expression was absent in multiple tissues of homozygous mutant neonate mice, while the protein was highly expressed in the brain, spleen and intestine in control neonate mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Bloc1s2<->,
  • Bloc1s2<->,
  • BLOS2-KO,
  • BLOS2-KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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