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Allele : Pon3<tm1Dmsh> paraoxonase 3; targeted mutation 1, Diana M Shih

Primary Identifier  MGI:5825222 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pon3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced exon 4. Western blot analysis confirmed the absence of protein expression in the liver. Lovastatinase activity is absent in liver homogenates of homozygous mutant mice, indicating complete loss of enzymatic activity.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pon3KO,
  • Pon3KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories