| Primary Identifier | MGI:5825293 | Allele Type | Targeted |
| Attribute String | Constitutively active | Gene | Scn5a |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 13 was modified such that an S571E muatation was created in the translated peptide. LoxP sites were inserted in intron 9 and intron 13. An FRT site flanked neomycin resistance gene cassette was inserted between exon 13 and the loxP site. The neo cassette was removed through flp-mediated recombination. The substituted glutamic acid mimics phosphorylated serine. |
