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Allele : Erc2<tm1Ksak> ELKS/RAB6-interacting/CAST family member 2; targeted mutation 1, Kenji Sakimura

Primary Identifier  MGI:5827585 Allele Type  Targeted
Gene  Erc2 Transmission  Germline
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  An FRT site flanked neomycin resistance gene cassette was inserted into intron 2. Exon 2 was targeted with a codon change: an S45A (TCT to GCC) mutation. This mutation creates a diagnostic MscI restriction site and changes serine 45 to an alanine, thus preventing phosphorylation of the peptide at that position.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • CAST-S45A,
  • CAST-S45A,
  • CAST<S45A>,
  • CAST<S45A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories