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Allele : Tg(MMTV-KRAS*G12V)3025Mrl transgene insertion 3025, Merck Research Laboratory
Primary Identifier  MGI:5827748 Allele Type  Transgenic
Attribute String  Constitutively active, Humanized sequence, Inserted expressed sequence Gene  Tg(MMTV-KRAS*G12V)3025Mrl
Strain of Origin  C57BL/6 x SJL Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of the mouse mammary tumor virus long terminal repeat (MMTV LTR), 5'-untranslated region from the HaSv, sequences encoding oncogenically mutated (glycine to valine at codon 12) human Kirsten (Ki)-rasB, and SV40 polyadenylation sequence. Highest level of transgene expression is in mammary tissue and no expression is seen in the kidney, liver or spleen.
  • mutations:
  • Insertion
  • synonyms:
  • MMTV-Ki-rasB,
  • MMTV-Ki-rasB
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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