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Allele : Nkx2-5<tm2.1Mwc> NK2 homeobox 5; targeted mutation 2.1, Mauro W Costa
Primary Identifier  MGI:5828833 Allele Type  Targeted
Attribute String  Not Specified Gene  Nkx2-5
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  This allele has a C to G point substitution that changes isoleucine to methionine at amino acid 183 in the homeodomain region, equivalent to I184 in human. The loxP-flanked neomycin cassette in the 3-prime UTR was excised by crossing to a cre deleter strain.
  • mutations:
  • Single point mutation
  • synonyms:
  • Nkx2-5Mdelta,
  • Nkx2-5Mdelta
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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