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Allele : Nkx2-5<tm3.1Mwc> NK2 homeobox 5; targeted mutation 3.1, Mauro W Costa

Primary Identifier  MGI:5828836 Allele Type  Targeted
Attribute String  Not Specified Gene  Nkx2-5
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  This allele has an ATC to CCA change that replaces isoleucine with proline at amino acid 183 in the homeodomain region, equivalent to I184 in human. The loxP-flanked neomycin cassette in the 3-prime UTR was excised by crossing to a cre deleter strain.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Nkx2-5Pdelta,
  • Nkx2-5Pdelta
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories