Primary Identifier | MGI:5829195 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr39 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 1500 bp deletion was introduced by CRISPR/cas9 endonuclease mediated genome editing 4 kb upstream of the Nr4a1 transcription start site in the Nr4a1 super enhancer (se) sub-domain E2. The deletion spans 101,262,166-101,263,744 (GRCm38/mm10). Nr4a1 gene expression is not altered. |