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Allele : Foxc2<tm1.1(cre/ERT2)Rssr> forkhead box C2; targeted mutation 1.1, R Sathish Srinivasan
Primary Identifier  MGI:5829561 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Foxc2
Transmission  Germline Strain of Origin  C57BL/6
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting vector with a cDNA sequence encoding the CreER fusion gene, followed by a frt-flanked neomycin selection cassette replaced the open reading frame of the Foxc2 gene via homologouse recombination in C57BL/6-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts, and chimeric males were bred with C57BL/6 for germline transmission. At some point, they were bred with ROSA26::FLPe mice (on a C57BL/6J genetic background) for germline deletion of the neo selection cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Foxc2<CreERT2>,
  • Foxc2<CreERT2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

5 Publication categories





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