Primary Identifier | MGI:5888920 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Gfra1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted upstream of the coding sequence the human GFRA1 cDNA with a transmembrane domain instead of the GPI anchor. A self-excising floxed neomycin resistance cassette is lacking in the final allele. Endogenous gene expression is disrupted. |