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Allele : Mecp2<tm5.1Joez> methyl CpG binding protein 2; targeted mutation 5.1, Zhaolan Zhou
Primary Identifier  MGI:5896330 Allele Type  Targeted
Attribute String  Epitope tag, No functional change Gene  Mecp2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct is designed to insert a loxP-flanked neomycin (neo) resistance cassette upstream of exon 4 of the gene. A 23 amino acid Tavi tag, which allows MECP2 protein to be biotinylated in the presence of E. coli biotin ligase, BirA, is introduced immediately upstream of Mecp2 stop codon. Cre-mediated recombination removed the floxed neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • MeCP2<Tavi>,
  • MeCP2<Tavi>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories





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