| Primary Identifier | MGI:5888871 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Nradd |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites were inserted to flank exon 2. A frt-flanked neomycin selection cassette was removed via Flp-mediated recombination, and subsequent Cre-mediated recombination deleted exon 2 to generate the null allele. Western blot analysis confirmed the absence of protein expression in spleen tissue of adult homozygous mutant mice. |
