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Allele : Trem2<tm1c(EUCOMM)Wtsi> triggering receptor expressed on myeloid cells 2; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5897643 Allele Type  Targeted
Attribute String  Conditional ready Gene  Trem2
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 48543421 of Chromosome 17 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted upstream of exon 4 at position 48544785. A "conditional ready" (floxed) allele is created by flp recombinase expression in mice carrying this allele.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories