| Primary Identifier | MGI:5897440 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Rdh10 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into intron 2 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 4. This creates a conditional-ready allele with exons 3 and 4 floxed. Through cre-mediated recombination these two exons, coding for the active site of the enzyme, were deleted, also causing a frameshift in the downstream exons. This creates a null allele. |
