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Allele : Tg(Otp-cre)1Hzo transgene insertion 1, Huda Y Zoghbi

Primary Identifier	MGI:5897831	Allele Type	Transgenic
Attribute String	Recombinase	Gene	Tg(Otp-cre)1Hzo
Strain of Origin	FVB/N	Is Recombinase	true
Is Wild Type	false

molecularNote

BAC RP24-337G4 containing the Otp locus was modified by recombineering to replace the Otp coding sequence with a Cre-recombinase. This BAC also incorporates exons 2-4 of the Tbca gene; no other genes are incorporated. This modified BAC was microinjected into fertilized oocytes.

mutations:
Insertion

synonyms:
Otp-cre,
Otp-cre

earliestPublication:
Lu HC, et al. (2017) Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet 49(4):527-536

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

4 Publication categories

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