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Allele : Cybb<em1Hmal> cytochrome b-245, beta polypeptide; endonuclease-mediated mutation 1, Harry Malech

Primary Identifier  MGI:5902368 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cybb
Strain of Origin  NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/SzJ Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 genome engineering, Cybb is targeted with a specific single guide RNA (GGTACTTACAATGACAAAGA) targeted to exon 1. The mutation is identified as a 235 bp deletion encompassing all of exon 1 and 190 bp of the upstream Cybb promoter.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

2 Publication categories