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Allele : Fgfr2<tm2.1Sor> fibroblast growth factor receptor 2; targeted mutation 2.1, Philippe Soriano

Primary Identifier  MGI:5903019 Allele Type  Targeted
Attribute String  No functional change, Reporter Gene  Fgfr2
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector is designed to replace the stop codon in exon 19 of the Fgfr2 gene with a cassette containing a human HIST1H2BB gene [histone 1 H2bb] sequence, a viral 2A oligopeptide (T2A) that mediates ribosomal skipping, a red fluorescent protein (mCherry) sequence, and a new stop codon. An FRT-flanked neomycin resistance (neo) cassette was inserted in the intron upstream of exon 19. Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Fgfr2-mCherry,
  • Fgfr2-mCherry,
  • Fgfr2-T2A-H2B-mCherry,
  • Fgfr2-T2A-H2B-mCherry
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

11 Publication categories