|  Help  |  About  |  Contact Us

Allele : Atoh1<tm7.1Hzo> atonal bHLH transcription factor 1; targeted mutation 7.1, Huda Y Zoghbi

Primary Identifier  MGI:5903210 Allele Type  Targeted
Attribute String  Reporter Gene  Atoh1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
molecularNote  The enhanced green fluorescent protein (EGFP) is fused to the 3' end of the gene, which carries a S193A (TCC->GCC) mutation, followed by an FRT-flanked PGK-neomycin selection cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. GFP expression has been observed in cerebellar granule neurons, deep cerebellar nuclei, hindbrain nuclei, spinal cord interneurons, secretory intestinal cells, Merkel cells, and inner ear hair cells.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Atoh1-EGFP-S193A,
  • Atoh1-S193A,
  • Atoh1-S193A,
  • Atoh1-EGFP-S193A
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories