| Primary Identifier | MGI:5903429 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(TcraS106-1,TcrbS106-1)TS1SWAjca |
| Strain of Origin | C57BL/6 x BALB/c | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct expresses a T cell receptor raised against hemagglutinin (HA) from influenza virus A/SW/33(SW), which contains an analog of the S1 determinant that differs from S1 by 2 substitutions, R to K at residue 113 and E to T at residue 120, isolated from hybridoma S106-1. This receptor is encoded by TCR Valpha8.3 and Vbeta10, and has a much lower affinity for the original S1 determinant than does Tg(Tcra/Tcrb)1Vbo . |
