| Primary Identifier | MGI:5910374 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Acox3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences ATGTCCAGACAAGCTGACAG, TTTTGTTAGGACTCTTACCA, GCTTAAGCCGCTGTTCCCAG and GTCACACCCTGAGAGACCCG, which resulted in a 687 bp deletion beginning at Chromosome 5 positive strand position 35,594,039 bp and ending after 35,594,725 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000185499 (exon 8) and 598 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 231 and early truncation 21 amino acids later. |
