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Allele : Tnfaip3<tm1.1Vmd> tumor necrosis factor, alpha-induced protein 3; targeted mutation 1.1, Vishva M Dixit

Primary Identifier  MGI:5908198 Allele Type  Targeted
Gene  Tnfaip3 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  A cysteine to alanine mutation was inserted at position 103 (C103A; TGC to GCC) in exon 3 and a floxed neo cassette was inserted in intron 2 at position chr10:18729002 (NCBI37/mm9) via homologous recombination. Cre mediated recombination removed the neo cassette. The mutation inactivates OTU catalytic activity.
  • mutations:
  • Single point mutation
  • synonyms:
  • C103A,
  • Tnfaip3<Otu>,
  • C103A,
  • Tnfaip3<Otu>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories