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Allele : Tnfaip3<tm3.1Vmd> tumor necrosis factor, alpha-induced protein 3; targeted mutation 3.1, Vishva M Dixit

Primary Identifier  MGI:5908200 Allele Type  Targeted
Gene  Tnfaip3 Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  A tyrosine to alanine mutation and a phenylalanine to alanine mutation were inserted at position 599 and 600 (Y599A and F600A; TATTTT to GCTGCA) in exon 7 and an FRT flanked neo cassette was inserted at position chr10:18724150 (NCBI37/mm9) via homologous recombination. Flp mediated recombination removed the neo cassette. The mutations compromise ZnF4 ubiquitin binding.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Tnfaip3<z4Ub>,
  • Tnfaip3<z4Ub>,
  • Y599A/F600A,
  • Y599A/F600A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories