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Allele : Ubap2<em1(IMPC)J> ubiquitin-associated protein 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:5910359 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ubap2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GAACGACCTGCAGCTCAGGT, TCTATAGCATGAATATCTGT, GTAGAGTCTATACCACTAAG and CTTGGCATACTAACTGCAGT, which resulted in a 437 bp deletion beginning at Chromosome 4 negative strand position 41,229,880 bp, and ending after 41,229,444 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001205355 (exon 5) and 283 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 96 and early truncation 221 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories