| Primary Identifier | MGI:5910441 | Allele Type | Targeted |
| Attribute String | Dominant negative, Humanized sequence | Gene | Fgf9 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was targeted with a G>A point mutation and a neomycin resistance gene cassette was inserted into intron 2. The mutation changes codon 99 from serine to asparagine (p.Ser99Asp). This mimics a mutation found in human multiple synostoses syndrome (SYNS) patients. RT-qPCR confirmed that this allele was expressed at the same level as wild-type. |
