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Allele : Runx3<tm4.1Yg> runt related transcription factor 3; targeted mutation 4.1, Yoram Groner

Primary Identifier	MGI:5911699	Allele Type	Targeted
Attribute String	Reporter	Gene	Runx3
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

An AFP-lox-PGK/neo-lox cassette at the initiator ATG of the P1-transcription unit was inserted via homologous recombination in ES cells. Floxed neo gene was subsequently removed by mating cre expressing mice.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Runx3-P1-AFP,
Runx3-P1-AFP

earliestPublication:
Levanon D, et al. (2011) Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function. EMBO Mol Med 3(10):593-604

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

8 Publication categories

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