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Allele : Col1a1<tm2(tetO-GFP/RNAi:Smc1a)Iaai> collagen, type I, alpha 1; targeted mutation 2, Iannis Aifantis

Primary Identifier  MGI:5911565 Allele Type  Targeted
Attribute String  Inducible, Knockdown, Reporter Gene  Col1a1
Transmission  Germline Strain of Origin  Not Specified
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  A construct containing a tetracycline promoter and a GFP fusion with a Mir30-based short hairpin sequence targeting Smc1a (Smc1a-3921) was inserted in the 3' UTR. Following tetracycline induced expression of the RNAi expression of Smc1a is strongly reduced and expression of associated protein members of the cohesin complex are also reduced.
  • mutations:
  • Insertion
  • synonyms:
  • Smc1a<(shRNA)>,
  • Smc1a<(shRNA)>
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories