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Allele : Dbn1<tm1c(KOMP)Wtsi> drebrin 1; drebrin 1; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5908152 Allele Type  Targeted
Attribute String  Conditional ready Gene  Dbn1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 55628889 of Chromosome 13 upstream of exon 1 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene cassette under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 6 at position 55631060. The critical exons are thus flanked by loxP sites. The lacZ and neo cassettes were removed through flp-mediated recombination, creating a conditional-ready allele with exons 1-6 floxed.
  • mutations:
  • Insertion
  • synonyms:
  • DBN<loxp>,
  • DBN<loxp>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories