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Allele : Apoe<em2(APOE*)Adiuj> apolipoprotein E; endonuclease-mediated mutation 2, MODEL-AD Center
Primary Identifier  MGI:5907023 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Apoe
Strain of Origin  B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj>/J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-Cas9 methodology introduced a p.R130C point mutation into the human APOE protein carried by the Apoetm1.1(APOE*4)Adpmc allele.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • APOE<epsilon3>,
  • APOE<epsilon3>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

23 Publication categories





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