Primary Identifier | MGI:5908273 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Tacr1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The coding region of Tacr1 in exon2 was replaced by a cre/ERT2 cassette and a loxP-flanked neo selection cassette by homologous recombination in ES cells. Correctly targeted ES cell clones were injected into C57BL/6 blastocysts. The neo-cassette was deleted by Cre-mediated excision. |