| Primary Identifier | MGI:5904959 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Crkl |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| molecularNote | The L1L2_Bact_P cassette was inserted at position 17286305 of Chromosome 16 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 2 at position 17287491. Exon 2 is thus flanked by loxP sites. A null/knockout allele was created cre recombinase expression in mice carrying this allele to remove the loxP-flanked critical exon 2. |
