|  Help  |  About  |  Contact Us

Allele : Tg(tetO/Prnp-MAPT)769Tli transgene insertion 769, Tong Li

Primary Identifier  MGI:5908815 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(tetO/Prnp-MAPT)769Tli
Strain of Origin  (C57BL/6 x SJL)F2 Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The transgenic construct contains sequence encoding a four-repeat domain of human MAPT protein (TauRD, Q244-E372) under the control of the mouse Prnp gene promoter and the tetO, tetracycline-responsive regulatory element (from the moPrP-tetP vector, 42-bp tet operator sequence copies followed by the constitutively active, minimal human cytomegalovirus promoter).
  • mutations:
  • Insertion
  • synonyms:
  • TetO-TauRD,
  • TauRD,
  • Tau4R,
  • Tau4R,
  • TauRD,
  • TetO-TauRD
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories