| Primary Identifier | MGI:5905765 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-Rest*)474Ysai |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A dominant-negative mutant neuron-restrictive silencer factor cDNA is under the control of the cardiac-specific alpha-MHC promoter. Two lines, 471 and 474, were generated. mRNA is expressed at a level 27-fold higher than endogenous mRNA in this line. Western blot confirmed that expression is restricted to the heart, though weak expression is seen in the lung. |
