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Allele : Cfap157<tm1c(EUCOMM)Hmgu> cilia and flagella associated protein 157; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH

Primary Identifier  MGI:5907282 Allele Type  Targeted
Attribute String  Conditional ready Gene  Cfap157
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 32671182 of Chromosome 2 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 2 at position 32671954. Exon 2 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking exon 2.
  • mutations:
  • Insertion
  • synonyms:
  • Cfap157<ex2flox>,
  • Cfap157<ex2flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories