Primary Identifier | MGI:5908730 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Alb-Selp)9Rpmc |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains cDNA encoding the entire extracellular domain of mouse Selp fused to a C-terminal 8-residue epitope for the Ca2+ dependent mAb HPC4, under the control of the mouse Alb, albumin, gene promoter, and a 3' bovine growth hormone poly(A) signal sequence. Founder mice stably express approximately 3.5 higher levels of the protein in plasma. |